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The improved use of diagnostic tools has enhanced the flexibility to determine the infection early, the guidelines observe. These embody blood tests, cultures and computed tomography (CT) imaging. Because among the methods are invasive – comparable to taking a culture straight from the lungs – physicians usually are reluctant to proceed. Because the infection is so deadly, physicians needs to be aggressive in diagnosing patients suspected of getting the infection, Dr. Patterson notes. Additionally, new extra-efficient and better-tolerated antifungal medications, or versions of current medications (e.g. prolonged release) have improved care, together with isavuconazole and posaconazole. In some instances, mixture therapy with voriconazole and an echinocandin is really helpful for certain patients at highest danger. Because invasive aspergillosis is so deadly, the guidelines recommend some patients at highest danger be treated with antifungals to prevent infection, including these with neutropenia and graft versus host disease (GVHD). Another prevention strategy is the use of particular filtration methods for hospitalized immunosuppressed patients.